作者: Carmen Pueyo , Manuel Ruiz-Rubio
DOI: 10.1007/978-1-4613-2147-7_3
关键词:
摘要: The evidence that most animal carcinogens are also mutagens,(20,24) strongly suggesting DNA is the ultimate target of carcinogenic activation, has been an important support somatic mutation theory etiology cancer. recent demonstration a single point mutation, GC to TA transversion, leads activation human oncogene(30,36) in agreement with this suggestion.