Pharmacokinetics Comparison of 132-Hydroxy-Bacteriopheophorbid-A Methyl Ester and Octa-α-Butyloxy-Zinc Phthalocyanine in Mice Bearing Lewis Lung Carcinoma
作者： M. S. Ismail , C. Dressler , B. Röder , H. Weitzel , H.-P. Berlien
DOI: 10.1007/978-3-642-60306-8_47
关键词:
摘要: The pharmacokinetics of 132-hydroxy-bacteriopheophorbid-a methyl ester (132-OH-BPME) and octa-α-butyloxy-zinc phthalocyanme (8-α-bo-Zn-Pc) were studied in mice bearingLewis lung carcinoma. Absorption spectroscopy was used to measure the photosensitizers concentrations. High 132-OH-BPME 8-α-bo-Zn-Pc uptakes recorded parenchymatous organs (liver, lung), with long retention. malignant tissues accumulated more than 20 folds at all incubation times. concentrations skin muscle lower any time period, but also, retained longer until 168h. PDT will be effective 8-α-bo-ZnPc since it is higher tissues.
springer.com
sci-hub.st 参考文章(15)
R. BIOLO, G. JORI, J. C. KENNEDY, P. NADEAU, R. POTTIER, E. REDDI, G. WEAGLE, A comparison of fluorescence methods used in the pharmacokinetic studies of Zn(II)phthalocyanine in mice. Photochemistry and Photobiology. ,vol. 53, pp. 113- 118 ,(1991) , 10.1111/J.1751-1097.1991.TB08475.X
Takashi Yano, Tohru Uozumi, Keiichi Kawamoto, Kazutoshi Mukada, Jun Onda, Akihiro Ito, Nariaki Fujimoto, Photodynamic therapy for rat pituitary tumor in vitro and in vivo using pheophorbide-a and white light Lasers in Surgery and Medicine. ,vol. 11, pp. 174- 182 ,(1991) , 10.1002/LSM.1900110212
Masoud Panjehpour, Rick E. Sneed, Donita L. Frazier, Mary Ann Barnhill, Sherrie F. O'Brien, William Harb, Bergein F. Overholt, Quantification of phthalocyanine concentration in rat tissue using laser-induced fluorescence spectroscopy. Lasers in Surgery and Medicine. ,vol. 13, pp. 23- 30 ,(1993) , 10.1002/LSM.1900130107
Kunihisa IWAI, Shuichi KIMURA, Efficiency of Pheophorbide-Dimer in Photodynamic Therapy of Mouse Tumor Journal of Clinical Biochemistry and Nutrition. ,vol. 5, pp. 145- 153 ,(1988) , 10.3164/JCBN.5.145
WS Chan, CML West, JV Moore, IR Hart, None, Photocytotoxic efficacy of sulphonated species of aluminium phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumours. British Journal of Cancer. ,vol. 64, pp. 827- 832 ,(1991) , 10.1038/BJC.1991.408
P. T. Chatlani, J. Bedwell, A. J. MacRobert, H. Barr, P. B. Boulos, N. Krasner, D. Phillips, S. G. Bown, Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon. Photochemistry and Photobiology. ,vol. 53, pp. 745- 751 ,(1991) , 10.1111/J.1751-1097.1991.TB09887.X
Beate Roeder, Cathrin Dressler, B. Fuchs, Roland Hagemann, Hans-Peter Berlien, Christian Nowak, Joerg G. Moser, Pharmakokinetics of 132-hydroxy-bacteriopheophorbide: a methyl ester studied by fluorescence spectroscopy on Lewis lung carcinoma bearing mice Photodynamic Therapy of Cancer. ,vol. 2078, pp. 427- 437 ,(1994) , 10.1117/12.168685
Masoud Panjehpour, Rick E. Sneed, Donita L. Frazier, Mary Ann Barnhill, Sherrie O'Brien, Bill Harb, Bergein F. Overholt, Laser-induced fluorescence quantitation of choloroaluminum phthalocyanine tetrasulfonate concentration in rat tissue Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy. ,vol. 1645, pp. 171- 179 ,(1992) , 10.1117/12.60940
M. C. Berenbaum, R. Bonnett, E. B. Chevretton, S. L. Akande-Adebakin, M. Ruston, Selectivity ofmeso-tetra(hydroxyphenyl)porphyrins and chlorins and of photofrin II in causing photodamage in tumour, skin, muscle and bladder. The comcept of cost-benefit in analysing the results Lasers in Medical Science. ,vol. 8, pp. 235- 243 ,(1993) , 10.1007/BF02547845
E Reddi, G Lo Castro, R Biolo, G Jori, Pharmacokinetic studies with zinc(II)-phthalocyanine in tumour-bearing mice. British Journal of Cancer. ,vol. 56, pp. 597- 600 ,(1987) , 10.1038/BJC.1987.247