Prospects of boswellic acids as potential pharmaceutics

摘要: Boswellic acids have long been considered the main bioactive components of frankincense, and many studies in vitro animals as well several clinical confirmed their various bioactivities. In particular, a large number mechanistic anti-inflammatory antitumor activities. However, not every boswellic acid exhibits satisfactory pharmacological performance, which depends on chemical structure functional groups acid. To enhance values acids, derivatization has specifically applied with aim discovering more active derivatives BAs. addition, preliminary pharmacokinetic these compounds using standard methods show poor bioavailability humans rodents, led to questions relevance potentially limits use practice pharmaceutical development. improve effects, some approaches shown improvements effectiveness, new formula compatibility approach is very reasonable method for improving acids.