Multifunctional nanoscale strategies for enhancing and monitoring blood vessel regeneration.
作者： Eunna Chung , Laura M. Ricles , Ryan S. Stowers , Seung Yun Nam , Stanislav Y. Emelianov
DOI: 10.1016/J.NANTOD.2012.10.007
关键词:
摘要: Nanomedicine has great potential in biomedical applications, and specifically regenerative medicine vascular tissue engineering. Designing nanometer-sized therapeutic diagnostic devices for engineering applications is critical because cells experience respond to stimuli on this spatial scale. For example, nanoscaffolds, including nanoscalestructured or nanoscale surface-modified scaffolds, can influence cell alignment, adhesion, differentiation promote better endothelization. Furthermore, contrast agents be extended the field of imaging monitor track stem understand process neovascularization. In addition, systems capable delivering biomolecules (e.g. peptides angiogenic genes/proteins) behavior, function, phenotype blood vessel regeneration. This review will focus nanomedicine strategies applied particular, some latest research pertaining tracking using agents, nanodelivery bioactive molecules regeneration discussed. overlap between these three areas their synergistic effects examined as related
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