Therapeutic effects of the Sp1 inhibitor mithramycin A in glioblastoma
作者： Janina Seznec , Björn Silkenstedt , Ulrike Naumann
DOI: 10.1007/S11060-010-0266-X
关键词:
摘要: … MitA inhibits binding of the transcription factor Sp1 to its promoters, leading to gene … via inhibition of Sp1 and, in consequence, by disruption of the Sp1/Smad7 complex [17–19]. …
springer.com
sci-hub.se 
researchgate.net 参考文章(47)
Wolfgang Wick, Michael Platten, Michael Weller, Glioma Cell Invasion: Regulation of Metalloproteinase Activity by TGF-β Journal of Neuro-oncology. ,vol. 53, pp. 177- 185 ,(2001) , 10.1023/A:1012209518843
Hartwig Wolburg, Wolfgang Wick, Gesa Rascher, Mathias Bähr, Ulrike Naumann, Emmanuel Conseiller, Michael Weller, Sebastian Kügler, Jörg B. Schulz, Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand. Cancer Research. ,vol. 61, pp. 5833- 5842 ,(2001)
Hans Georg Rammensee, Johannes Dichgans, Steffen Aulwurm, Hans Jörg Bühring, Ulrike Naumann, Michael Platten, Stefan Z. Lutz, Felix Bischof, Manuel A. Friese, Michael Weller, Alexander Steinle, Alexander Steinle, MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas Cancer Research. ,vol. 63, pp. 8996- 9006 ,(2003)
Gopalakrishnan M. Venkataraman, Dominic Suciu, Veronika Groh, Jeremy M. Boss, Thomas Spies, Promoter Region Architecture and Transcriptional Regulation of the Genes for the MHC Class I-Related Chain A and B Ligands of NKG2D Journal of Immunology. ,vol. 178, pp. 961- 969 ,(2007) , 10.4049/JIMMUNOL.178.2.961
Mirjam Hermisson, Andrea Klumpp, Wolfgang Wick, Jorg Wischhusen, Georg Nagel, Wynand Roos, Bernd Kaina, Michael Weller, O6‐methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells Journal of Neurochemistry. ,vol. 96, pp. 766- 776 ,(2006) , 10.1111/J.1471-4159.2005.03583.X
George Koutsodontis, Dimitris Kardassis, Inhibition of p53-mediated transcriptional responses by mithramycin A. Oncogene. ,vol. 23, pp. 9190- 9200 ,(2004) , 10.1038/SJ.ONC.1208141
Ruo-Kai Lin, Chun-Hua Hsu, Yi-Ching Wang, Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells Anti-Cancer Drugs. ,vol. 18, pp. 1157- 1164 ,(2007) , 10.1097/CAD.0B013E3282A215E9
A. HLOBILKOVA,, J. EHRMANN, P. KNIZETOVA, V. KREJCI, O. KALITA, Z. KOLAR, Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression. Neoplasma. ,vol. 56, pp. 284- 290 ,(2009) , 10.4149/NEO_2009_04_284
Lorenz Rieger, Michael Weller, Antje Bornemann, Martin Schabet, Johannes Dichgans, Richard Meyermann, BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study Journal of the Neurological Sciences. ,vol. 155, pp. 68- 75 ,(1998) , 10.1016/S0022-510X(97)00277-3
U Naumann, H Huang, H Wolburg, J Wischhusen, S Weit, H Ohgaki, M Weller, PCTAIRE3: a putative mediator of growth arrest and death induced by CTS-1, a dominant-positive p53-derived synthetic tumor suppressor, in human malignant glioma cells. Cancer Gene Therapy. ,vol. 13, pp. 469- 478 ,(2006) , 10.1038/SJ.CGT.7700917