Nutcracker phenomenon and idiopathic IgA nephropathy

作者: M. B. M. Mazzoni , G. P. Milani , C. Persico , A. Edefonti , E. A. Laicini

DOI: 10.1093/NDTPLUS/SFR108

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摘要: Sir, Entrapment of the left renal vein between aorta and superior mesenteric artery is a documented cause both postural proteinuria as well intermittent gross haematuria associated with flank pain. Idiopathic IgA nephropathy typically presents recurrent episodes haematuria, usually following an acute febrile illness. Rarely, disease microscopic mild proteinuria. We present first case caused by entrapment nephropathy. In 11-year-old boy proteinuria, ultrasonic Doppler disclosed entrapment: anteroposterior diameter at hilar portion divided that aortomesenteric was 13.3 (reference ≤ 4.0) peak flow velocity 15.1 4.0). Two years later, three diarrhoea were followed not The kidney biopsy showed diffuse mesangial proliferation matrix expansion. diagnosis made on immunofluorescence microscopy, which demonstrated isolated prominent globular deposits IgA, C3 IgG in mesangium. The link documented. Furthermore, are recognized causes haematuria. There five reported patients affected idiopathic [1–4]. A 12-year-old German girl found to have [1]. Similarly, 9-year-old Korean [2] 25-year old Taiwanese woman pain [3]. Left also 20-year-old 22-year-old Japanese man, who, context pharyngitis, developed tendency persisting [4]. In addition, two children 13-year-old Henoch–Schonlein syndrome [5]. Finally, 10-year-old clinically characteristic rapidly resolving form for 26 months entrapment; subsided accordance radiological improvement [6]. Our patient concurrent existence nephropathy. Renal venous congestion may induce been implicated damage. So, causal relationship cannot be ruled out. Further investigations necessary detect this correlation.

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