One-Step Synthesis of Monolithic Silica Nanocomposites in Fused Silica Capillaries

摘要: The ideal way to prepare efficient, yet robust stationary phases for microanalytical high-resolution methods such as capillary chromatography and electrochromatography remains be defined. In this contribution a one step sol-gel process is proposed the production of monolithic, macroporous nanocomposite in fused silica capillaries, which require no additional derivatization, since they already bear interactive (C8) moieties. effect catalyst, water content, pH, well that certain additives on monolith formation porosity investigated. Volume shrinkage tendency crack were major obstacles overcome. Homogeneous could produced by applying pH gradient during sol formation, thereby changing catalytic principle from acidic (0.1 M HCl) basic (gradual OH− consequence hydrolysis N-methylformamide). Gelation/coacervation suchgels induced addition N,N-diethylamine. content was determined decisive pore with 250% amount theoretically needed complete all precursors giving optimal results. volume problem xerogel resolved integrating dialkyldialkoxysilane units (dimethyldiethoxysilane 35 mol%) into network.