Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
作者： Mohit Narwal , Jarkko Koivunen , Teemu Haikarainen , Ezeogo Obaji , Ongey E. Legala
DOI: 10.1021/JM401463Y
关键词:
摘要: … Inhibitors were soaked for 24 h into the crystals in the well solution supplemented with the compound (100 μM) and 250 mM NaCl. The crystals were dipped into cryosolution …
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