Bubonic leishmaniasis: a common manifestation of Leishmania (Viannia) braziliensis infection in Ceara, Brazil.

摘要: Abstract Enlarged regional lymph nodes have been reported to accompany the cutaneous lesions of Leishmania (Viannia) braziliensis (= L. braziliensis). A survey in Ceara State, Brazil indicated that 77% persons (456 595) with parasitologically confirmed leishmaniasis lymphadenopathy addition skin lesions. group 169 recently diagnosed and measuring ≥ 2 cm diameter (mean = 3.6 cm, maximum 10.5 cm) underwent detailed clinical examination. Lymphadenopathy preceded more than two-thirds these, on average by two weeks. Cultures node aspirates yielded frequently (86%) cultures (53%) or biopsies (74%). Parasites were isolated from peripheral blood one patient. Persons gave a history fever had enlarged livers spleens often comparison 50 but no lymphadenopathy. intense leishmanin reactions lymphocyte proliferation following stimulation specific antigens, whereas without higher frequency previous infection. Isolates parasites both groups identified as braziliensis. These data demonstrate early spread beyond suggest differences host immunity between Leishmaniasis should be considered cases unexplained endemic areas.