Leishmania: a Parasite on the Move

摘要: During the past decade, there has been an increase in numbers of new cases, spread disease into regions, and even appearance clinical syndromes. This resurgence leishmaniasis reflects remarkable adaptability Leishmania parasite to changing conditions, such as those resulting from economic development, human modification environment, population movements. In visceral leishmaniasis, or kala-azar, is infection reticuloendothelial cells throughout body particularly liver, spleen, bone marrow, lymphoid tissue. cutaneous replication confined primarily skin. Treatment required for persons with clinically apparent mucocutaneous cases which spontaneous healing slow, lesions involve face, due species that can cause diffuse leishmaniasis. The gold standard treatment pentavalent antimony given intravenously intramuscularly at a dose 20 mg/kg/day minimum days. Visceral HIV-infected associated higher levels parasitemia than seen non-HIV-infected persons, sand flies readily acquire parasites coinfected persons. Measures control Teresina have focused on identifying killing infected dogs, application insecticide neighborhoods surrounding frank kala-azar. High among priorities research development methods predicting occurrence outbreaks establishment foci transmission.