Ultrasonic-assisted self-assembly of monolayer graphene oxide for rapid detection of Escherichia coli bacteria

作者: Jingbo Chang , Shun Mao , Yang Zhang , Shumao Cui , Guihua Zhou

DOI: 10.1039/C3NR00141E

关键词:

摘要: Due to potential risks the environment and human health arising from pathogens/chemical contaminants, novel devices are being developed for rapid precise detection of those contaminants. Here, we demonstrate highly sensitive selective field-effect transistor (FET) sensor Escherichia coli (E. coli) bacteria using thermally reduced monolayer graphene oxide (TRMGO) sheets as semiconducting channels. The (GO) assembled on aminoethanethiol (AET)-functionalized gold (Au) electrodes through electrostatic interactions with ultrasonic assistance. Anti-Escherichia (anti-E. antibodies used receptors E. cells integrated FET device covalent bonding Au nanoparticles GO surface. TRMGO shows great electronic stability high sensitivity a concentration low 10 colony-forming units (cfu) per mL. biosensing platform reported here is promising large-scale, sensitive, selective, low-cost, real-time bacteria.

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