Analysis of chemiotherapeutic protocols efficiency in therapy of advanced non small cell lung cancer.
作者： Enver Zerem , Almir Fajkic , Miralem Music , Alma Mekic-Abazovic
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摘要: original paper sUMMarY Aim: To confirm the efficiency and toxicity of two chemiotherapeutic protocols - Cisplatin gemcitabin (CDDp, gemcitabin) Cisplatin, Vinorelbin (CDD p, Vinorelbin) in advanced non-small cell lung cancer (nsClC). patients methods: Retrospectively were analyzed treated a total 60 (two groups with 30 patients) for or metastatic nsClC during period from January 2005 to 2007. The CDD CDDp, four weeks. chemiotherapy was administered intravenously. Results: Although registered response rates bit lower than previously published trials, they not significantly different arms (26% vs. 15%) (p=0,485). statistically therapeutic responses sD 44% CDDp , 93,3%) (p < 0,001) Os 10,83 % 21.00%) (p< 0.05). regimen has shown higher hematologic (9% 7%), toxicities (p=0.0029). Conclusion: this investigation patients, better profile. preferred could be gemcitabin.
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