Asymmetric synthesis of aziridine 2-phosphonates and azirinyl phosphonates from enantiopure sulfinimines

作者: Franklin A. Davis , William McCoull

DOI: 10.1016/S0040-4039(98)02331-4

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摘要: Abstract Enantiopure sulfinimine (S)- 4 was employed in a Darzens-type synthesis of aziridine 2-phosphonates (−)-7/(+)-8 wich were transformed into α-amino phosphonates (S)-11/(R)-12 and the first enantiopure examples azirinyl 13–15 .

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