Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities.
作者： Özdemir Doğan , Hakan Babiz , Ayşe Gül Gözen , Songül Budak
DOI: 10.1016/J.EJMECH.2011.03.037
关键词:
摘要: A set of new aziridinyl phosphonates (4a-g) were synthesized by using the Gabriel-Cromwell reaction and its modified version developed in this study their structures confirmed HRMS, IR, NMR spectra. All compounds screened for antibacterial activity. They all showed comparable moderate to good growth inhibitory activity reference ampicillin streptomycin.
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