Prospective evaluation of prognostic factors in patients with colorectal cancer undergoing curative resection.

摘要: Background and Objectives Streak type, defined by the presence of white streaks at advancing margin tumor invasion; focal dedifferentiation, seen as undifferentiated cancer cells with an infiltrative pattern invasive front; perineural invasion have been demonstrated to be prognostic factors in patients colorectal cancer. We performed a prospective study examine usefulness these features factors. Methods We reviewed total 391 who underwent curative surgery for between May 1997 June 1999. Of these, 50 multiple cancers were excluded, 341 finally entered into study. Results Of investigated, depth invasion, lymph node status, lymphatic venous growth streak significant univariate analysis. In multivariate analysis, factors. The survival was significantly poorer than that without both stage II III cancer. Conclusions Perineural status can used facilitate selection adjuvant chemotherapy should described routine pathology reports. J. Surg. Oncol. 2003;84:127–131. © 2003 Wiley-Liss, Inc.