Mortality and cardiovascular events are best predicted by low central/peripheral pulse pressure amplification but not by high blood pressure levels in elderly nursing home subjects: the PARTAGE (Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population) study.

摘要: Objectives The aim of the longitudinal PARTAGE study was to determine predictive value blood pressure (BP) and pulse amplification, a marker arterial function, for overall mortality (primary endpoint) major cardiovascular (CV) events, in subjects older than 80 years age living nursing home. Background Assessment indexes may be important evaluation CV risk very elderly frail subjects. Methods A total 1,126 (874 women) who were French Italian homes enrolled (mean age, 88 ± 5 years). Central (carotid) peripheral (brachial) amplification (PPA) calculated with help an tonometer. Clinical 3-day self-measurements BP conducted. Results During 2-year follow-up, 247 died, 228 experienced events. PPA predictor events this population. 10% increase associated 24% (p Conclusions In individuals homes, low from central arteries strongly predicts adverse effects. parameter could estimation improve diagnostic therapeutic strategies old, polymedicated persons. contrast, high is not higher or (Predictive Values Blood Pressure Arterial Stiffness Institutionalized Very Aged Population [PARTAGE]; NCT00901355)