Comparative Studies of Platelet Survival by Different Methods in the Rabbit

作者: SHIRLEY EBBE , MARIO BALDINI , JANET DONOVAN

DOI: 10.1182/BLOOD.V25.4.548.548

关键词:

摘要: Four methods for measuring the survival of homologous platelets in rabbits were studied: (1) transfusion nonradioactive platelet concentrates to thrombocytopenic recipients, (2) labeled vitro with Cr51-sodium chromate, (3) vivo P32-orthophosphate and (4) whole blood P32-orthophosphate. The time normal was 3-4 days. From comparison 3 using concentrates, following conclusions drawn. All a concentrate capable recirculating after transfusion. Labeling P32 or Cr51 did not damage platelets. About one-third immediately eluted from viable they transfused. Further exchange label occur significant degree either P32. (5) elute during storage (6) Studies rabbit had applicability predicting behavior human

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