C-Reactive Protein Levels Are Higher in Patients With Fusiform Intracranial Aneurysms: A Case-Control Study
作者： João Paulo Mota Telles , Nicollas Nunes Rabelo , Jefferson Rosi Junior , Manoel Jacobsen Teixeira , Eberval Gadelha Figueiredo
DOI: 10.1016/J.WNEU.2020.11.042
关键词:
摘要: Background Comprehending the risk factors that contribute to formation of fusiform aneurysms (FAs) might provide some insight into treatment and prevention strategies. This case-control study aimed compare levels serum C-reactive protein (CRP), as a biomarker, between patients with saccular intracranial aneurysms. Methods We retrospectively analyzed medical records from 2010 2019. Thirty-five were identified having FAs: 13 (37.1%) ruptured, 22 unruptured. An age-matched sample 70 controls (2:1) was obtained same records: 36 (51.4%) ruptured 34 Results Patients FAs had median CRP values 0.61 mg/dL (IQR: 1.5), compared 0.29 0.42) in (P Conclusions higher than controls, it constituted an independent predictor morphology for unruptured Inflammation be especially important factor FA growth, further studies could use this finding design new
sci-hub.st 参考文章(35)
Kostas N. Fountas, Anastasia Tasiou, Eftychia Z. Kapsalaki, Konstantinos N. Paterakis, Arthur A. Grigorian, Gregory P. Lee, Joe Sam Robinson, Serum and cerebrospinal fluid C-reactive protein levels as predictors of vasospasm in aneurysmal subarachnoid hemorrhage. Clinical article. Neurosurgical Focus. ,vol. 26, ,(2009) , 10.3171/2009.2.FOCUS08311
Flávio Ramalho Romero, Eduardo de Freitas Bertolini, Eberval G. Figueiredo, Manoel Jacobsen Teixeira, Serum C-reactive protein levels predict neurological outcome after aneurysmal subarachnoid hemorrhage. Arquivos De Neuro-psiquiatria. ,vol. 70, pp. 202- 205 ,(2012) , 10.1590/S0004-282X2012000300009
L. Z. CSAJBOK, K. NYLÉN, M. ÖST, H. SONANDER, B. NELLGÅRD, In-hospital C-reactive protein predicts outcome after aneurysmal subarachnoid haemorrhage treated by endovascular coiling. Acta Anaesthesiologica Scandinavica. ,vol. 59, pp. 255- 264 ,(2015) , 10.1111/AAS.12441
Juhana Frösen, Riikka Tulamo, Anders Paetau, Elisa Laaksamo, Miikka Korja, Aki Laakso, Mika Niemelä, Juha Hernesniemi, Saccular intracranial aneurysm: pathology and mechanisms Acta Neuropathologica. ,vol. 123, pp. 773- 786 ,(2012) , 10.1007/S00401-011-0939-3
Hirofumi Nakatomi, Hiromu Segawa, Atsushi Kurata, Yoshiaki Shiokawa, Kazuya Nagata, Hiroyasu Kamiyama, Keisuke Ueki, Takaaki Kirino, Clinicopathological Study of Intracranial Fusiform and Dolichoectatic Aneurysms: Insight on the Mechanism of Growth Stroke. ,vol. 31, pp. 896- 900 ,(2000) , 10.1161/01.STR.31.4.896
Seppo Juvela, Johanna Kuhmonen, Jari Siironen, C-reactive protein as predictor for poor outcome after aneurysmal subarachnoid haemorrhage Acta Neurochirurgica. ,vol. 154, pp. 397- 404 ,(2012) , 10.1007/S00701-011-1243-7
Tomohiro Aoki, Hiroharu Kataoka, Ryota Ishibashi, Hironori Nakagami, Kazuhiko Nozaki, Ryuuichi Morishita, Nobuo Hashimoto, Pitavastatin suppresses formation and progression of cerebral aneurysms through inhibition of the nuclear factor kappaB pathway. Neurosurgery. ,vol. 64, pp. 357- 366 ,(2009) , 10.1227/01.NEU.0000336764.92606.1D
Kazuo Kataoka, Mamoru Taneda, Toshiharu Asai, Akira Kinoshita, Mamoru Ito, Ryotaro Kuroda, Structural fragility and inflammatory response of ruptured cerebral aneurysms. A comparative study between ruptured and unruptured cerebral aneurysms. Stroke. ,vol. 30, pp. 1396- 1401 ,(1999) , 10.1161/01.STR.30.7.1396
Tomohiro Aoki, Masaki Nishimura, Hiroharu Kataoka, Ryota Ishibashi, Kazuhiko Nozaki, Nobuo Hashimoto, Reactive oxygen species modulate growth of cerebral aneurysms: a study using the free radical scavenger edaravone and p47phox−/− mice Laboratory Investigation. ,vol. 89, pp. 730- 741 ,(2009) , 10.1038/LABINVEST.2009.36
Nobutaka Horie, Nobuaki Takahashi, Shoji Furuichi, Katsuharu Mori, Masanari Onizuka, Keisuke Tsutsumi, Shobu Shibata, Giant fusiform aneurysms in the middle cerebral artery presenting with hemorrhages of different origins. Report of three cases and review of the literature. Journal of Neurosurgery. ,vol. 99, pp. 391- 396 ,(2003) , 10.3171/JNS.2003.99.2.0391