Predictors of treatment nonresponse in bipolar children and adolescents with manic or mixed episodes

摘要: Even though juvenile bipolar disorder (BD) is reported to be more treatment-resistant than adult BD, predictors of nonresponse are not well studied. The aim this study was address issue in a naturalistic sample children and adolescents with manic or mixed episodes treated under the condition routine clinical practice. This comprised 40 patients (19 females 21 males; mean age, 14.2 years; SD = 3.3; range, 7–18) Diagnostic Statistical Manual Mental Disorders—fourth edition (DSM-IV) diagnosis (n 23) 17). characteristics 20 considered treatment responders, according Clinical Global Impression—Improvement (CGI-I) scores, were compared those nonresponders. effect on probability analyzed using multiple stepwise logistic regression, backward procedure. Demographic variables (mean gender ratio, socioeconomic status),...