The purple non-sulfur bacterium Rhodopseudomonas palustris produces novel petrobactin-related siderophores under aerobic and anaerobic conditions

摘要: Many bacteria produce siderophores to bind and take up Fe(III), an essential trace metal with extremely low solubility in oxygenated environments at circumneutral pH. The purple non-sulfur bacterium Rhodopseudomonas palustris str. CGA009 is a metabolically versatile model organism high iron requirements that able grow under aerobic anaerobic conditions. Siderophore biosynthesis has been predicted by genomic analysis, however, siderophore structures were not identified. Here, we elucidate the structure of two novel from R. palustris: rhodopetrobactin A B. Rhodopetrobactins are structural analogues known petrobactin which Fe chelating moieties conserved, including 3,4-dihydroxybenzoate citrate substructure. In place spermidine linker groups petrobactin, rhodopetrobactins contain 4,4'-diaminodibutylamine one or both acetylated central amine. We analyse production different growth modes show produced response limitation as well Evaluation chemical characteristics indicates they suited support acquisition variable oxygen light