Polarization-based non-staining cell detection

作者: M. Zhang , K. Ihida-Stansbury , J. Van der Spiegel , N. Engheta

DOI: 10.1364/OE.20.025378

关键词:

摘要: Polarization is an important characteristic of electromagnetic waves, which can not be detected by either the human visual system or traditional image sensors. Motivated various animal species with polarization vision as well prospect improving quality imaging systems, we are exploring potential for microscope imaging. The most powerful techniques molecule monitoring requires complex preprocessing labeling sample different dyes. In this paper, propose a cell detection method using without any need staining target samples chemical dye. motivation work to develop optical technique that simple and used on live cells. sensitivity studied in paper. A definition quantity called “polarization deviation” proposed order identify clearer difference between cells background. Based deviation method, three-parameter employed further simplify capture procedure label-free detection. color methodology based well-known space utilized represent captured information computer graphics.

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