Genetic approaches to a better understanding of bipolar disorder.
作者： James Offord
DOI: 10.1016/J.PHARMTHERA.2011.10.001
关键词:
摘要: Bipolar disorder is a disease which causes major disability. The has both manic and depressive component. Current standard of care consists atypical antipsychotics for the treatment mania, antidepressants depression, mood stabilizers maintenance euthymia. molecular mechanisms cause are not well understood. Genome wide association studies have provided set genes linked to disease. These show linkage physiological neuroanatomical alterations also seen in bipolar disorder.
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