ADRENAL STEROIDS AND THE DEVELOPMENT OF OSTEOPOROSIS IN OOPHORECTOMISED WOMEN
作者： S.C. Manolagas , D.C. Anderson , R. Lindsay
DOI: 10.1016/S0140-6736(79)91663-5
关键词:
摘要: Abstract To explore the possibility that wide variation in bone loss among oophorectomised women might be due to differences adrenal androgens or their biosynthetic pathways, 18 (10 with very fast and 8 slow loss) were selected. Serum levels of nine steroids, including major cortisol, measured under basal conditions after overnight suppression followed by acute corticotropin stimulation. In addition, serum œstrone, œstradiol, dehydroepiandrosterone sulphate, sex-hormone-binding-globulin, corticosteroid binding globulin, urinary free cortisol measured. The only significant found who lost rapidly had significantly higher free-cortisol excretion (p
sci-hub.se 参考文章(28)
R. Lindsay, J.M. Aitken, L.B. Anderson, D.M. Hart, E.B. Macdonald, A.C. Clarke, LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN The Lancet. ,vol. 307, pp. 1038- 1041 ,(1976) , 10.1016/S0140-6736(76)92217-0
S. CATTANEO, G. FORTI, G. FIORELLI, U. BARBIERI, M. SERIO, A RAPID RADIOIMMUNOASSAY FOR DETERMINATION OF DEHYDROEPIANDROSTERONE SULPHATE IN HUMAN PLASMA Clinical Endocrinology. ,vol. 4, pp. 505- 512 ,(1975) , 10.1111/J.1365-2265.1975.TB01561.X
D H Marshall, R G Crilly, B E Nordin, Plasma androstenedione and oestrone levels in normal and osteoporotic postmenopausal women. BMJ. ,vol. 2, pp. 1177- 1179 ,(1977) , 10.1136/BMJ.2.6096.1177
B.E.C. Nordin, M.M. Young, B. Bentley, P. Ormondroyd, J. Sykes, LUMBAR SPINE DENSITOMETRY METHODOLOGY AND RESULTS IN RELATION TO THE MENOPAUSE Clinical Radiology. ,vol. 19, pp. 459- 464 ,(1968) , 10.1016/S0009-9260(68)80107-2
J. POORTMAN, J. A. C. PRENEN, F. SCHWARZ, J. H. H. THIJSSEN, Interaction of Δ5-Androstene-3β,17β-diol with Estradiol and Dihydrotestosterone Receptors in Human Myometrial and Mammary Cancer Tissue1 The Journal of Clinical Endocrinology and Metabolism. ,vol. 40, pp. 373- 379 ,(1975) , 10.1210/JCEM-40-3-373
PAUL C. MACDONALD, RAOUL P. ROMBAUT, PENTTI K. SIITERI, Plasma Precursors of Estrogen. I. Extent of Conversion of Plasma Δ4-Androstenedione to Estrone in Normal Males and Nonpregnant Normal, Castrate and Adrenalectomized Females The Journal of Clinical Endocrinology and Metabolism. ,vol. 27, pp. 1103- 1111 ,(1967) , 10.1210/JCEM-27-8-1103
S. C. MANOLAGAS, D. C. ANDERSON, DETECTION OF HIGH-AFFINITY GLUCOCORTICOID BINDING IN RAT BONE Journal of Endocrinology. ,vol. 76, pp. 379- 380 ,(1978) , 10.1677/JOE.0.0760379
H. C. Paassen, J. Poortman, I. H. C. Borgart-Creutzburg, J. H. H. Thijssen, S. A. Duursma, Oestrogen binding proteins in bone cell cytosol Calcified Tissue International. ,vol. 25, pp. 249- 254 ,(1978) , 10.1007/BF02010778
C. G. BEARDWELL, C. W. BURKE, C. L. COPE, URINARY FREE CORTISOL MEASURED BY COMPETITIVE PROTEIN BINDING Journal of Endocrinology. ,vol. 42, pp. 79- 89 ,(1968) , 10.1677/JOE.0.0420079
R. LINDSAY, J. R. T. COUTTS, D. M. HART, THE EFFECT OF ENDOGENOUS OESTROGEN ON PLASMA AND URINARY CALCIUM AND PHOSPHATE IN OOPHORECTOMIZED WOMEN Clinical Endocrinology. ,vol. 6, pp. 87- 93 ,(1977) , 10.1111/J.1365-2265.1977.TB01999.X