Reduced growth hormone releasing factor (GHRF)-like immunoreactivity and GHRF gene expression in the hypothalamus of aged rats.
作者： V. De Gennaro Colonna , M. Zoli , D. Cocchi , A. Maggi , P. Marrama
DOI: 10.1016/0196-9781(89)90164-2
关键词:
摘要: Growth hormone releasing factor-like immunoreactivity (GHRF-LI) and GHRF mRNA levels were evaluated in the hypothalamus of aged (24 months) young (3 rats by semiquantitative immunocytochemistry slot blot hybridization technique, respectively. Simultaneous detection reduced GHRF-LI as compared to counterparts demonstrates existence an impaired function GHRF-producing neurons.
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