Inhibition of growth of Chlamydia trachomatis by human gamma interferon.

摘要: Treatment of HEp-2 cell cultures with highly purified human gamma interferon before infection resulted in the reduction Chlamydia trachomatis (L2/434/Bu) infectious particle yield. Electron microscope studies showed that did not affect chlamydial conversion to reticulate bodies but influenced extent maturation elementary bodies. High concentrations (greater than 350 IU/ml) inhibited inclusion body formation and appearance aberrant Images