Occurrence of catecholaminergic nerve fibers in the human uveoscleral tissue in conditions of normal and raised intraocular pressure.

作者: Carlo Cavallotti , Nicola Pescosolido , Marco Artico , Elena Pacella , Daniela Cavallotti

DOI: 10.1023/A:1021173115883

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摘要: The distribution of catecholaminergic nerve fibers (CNF) in human uveoscleral tissue was studied six eyes with normal intraocular pressure and five increased pressure. had no visual field alterations the patients did not have anyglaucoma-related opticneuropathies. amount norepinephrine these structures also analysed. Catecholaminergic were detected by means fluorescence microscopy counted using quantitative analysis images. Our results demonstrate that occurrence (expressed Conventional Units = C.U.) is 15.4 ± 1.6 C.U. In pressure, values 12.2 1.2 Moreover, homogenates same evaluated found to be 21.7 1.3 μg/gr fresh weight This value decreased 18.8 1.1 conditions raised experiments, small number examined made it difficult draw general conclusions. However, role emphasized rich innervation. A decrease occurs when elevated. modifications parameters, involved sympathetic control aqueous humor outflow, may support hypothesis a possible relevant for different pathological conditions.

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