Adipose-Derived Stem Cells for Skin Regeneration
作者： Hiroshi Mizuno , Masaki Nambu
DOI: 10.1007/978-1-61737-960-4_33
关键词:
摘要: Intractable skin ulcers resulting from diabetes, ischemia and collagen diseases represent significant problems with few solutions. Cell-based therapy may hold promise in overcoming such disorders. In order to establish a suitable experimental model for the treatment of using stem cells, this chapter describes detailed methods for: (1) isolation cells adipose tissue, termed adipose-derived (ASCs), (2) preparing hybrid-type artificial dermis that consists type I sponge ASCs, (3) intractable Mitomycin C, (4) evaluating effect wound healing histologically. ASCs seeded onto are applied induced by topical application C. Histological evaluation after 1 2 weeks revealed an increase capillary density granulation thickness dermis. These findings suggest have positive on be useful tool future cell-based therapy.
springer.com
sci-hub.st 参考文章(11)
Harold Brem, Marjana Tomic-Canic, Cary Isaacs, Jan Young, H Paul Ehrlich, Clinical efficacy and mechanism of bilayered living human skin equivalent (HSE) in treatment of diabetic foot ulcers Surgical technology international. ,vol. 11, pp. 23- 31 ,(2003)
Jason R. Hanft, Maria S. Surprenant, Healing of chronic foot ulcers in diabetic patients treated with a human fibroblast-derived dermis. Journal of Foot & Ankle Surgery. ,vol. 41, pp. 291- 299 ,(2002) , 10.1016/S1067-2516(02)80047-3
Shigeru Ichioka, Sachio Kouraba, Naomoi Sekiya, Norihiko Ohura, Takashi Nakatsuka, Bone marrow-impregnated collagen matrix for wound healing: experimental evaluation in a microcirculatory model of angiogenesis, and clinical experience. British Journal of Plastic Surgery. ,vol. 58, pp. 1124- 1130 ,(2005) , 10.1016/J.BJPS.2005.04.054
Masaki Nambu, Satoko Kishimoto, Shingo Nakamura, Hiroshi Mizuno, Satoshi Yanagibayashi, Naoto Yamamoto, Ryuichi Azuma, Shin-ichiro Nakamura, Tomoharu Kiyosawa, Masayuki Ishihara, Yasuhiro Kanatani, Accelerated wound healing in healing-impaired db/db mice by autologous adipose tissue-derived stromal cells combined with atelocollagen matrix. Annals of Plastic Surgery. ,vol. 62, pp. 317- 321 ,(2009) , 10.1097/SAP.0B013E31817F01B6
Lee C Rogers, Nicholas J Bevilacqua, David G Armstrong, The use of marrow-derived stem cells to accelerate healing in chronic wounds. International Wound Journal. ,vol. 5, pp. 20- 25 ,(2008) , 10.1111/J.1742-481X.2007.00349.X
G. D. Gentzkow, S. D. Iwasaki, K. S. Hershon, M. Mengel, J. J. Prendergast, J. J. Ricotta, D. P. Steed, S. Lipkin, Use of Dermagraft, a Cultured Human Dermis, to Treat Diabetic Foot Ulcers Diabetes Care. ,vol. 19, pp. 350- 354 ,(1996) , 10.2337/DIACARE.19.4.350
Bernadette Aulivola, Major Lower Extremity Amputation Archives of Surgery. ,vol. 139, pp. 395- 399 ,(2004) , 10.1001/ARCHSURG.139.4.395
Masaki Nambu, Masayuki Ishihara, Shingo Nakamura, Hiroshi Mizuno, Satoshi Yanagibayashi, Yasuhiro Kanatani, Hidemi Hattori, Bonpei Takase, Takamitsu Ishizuka, Satoko Kishimoto, Yoshiko Amano, Naoto Yamamoto, Ryuichi Azuma, Tomoharu Kiyosawa, Enhanced healing of mitomycin C-treated wounds in rats using inbred adipose tissue-derived stromal cells within an atelocollagen matrix. Wound Repair and Regeneration. ,vol. 15, pp. 505- 510 ,(2007) , 10.1111/J.1524-475X.2007.00258.X
Gino Rigotti, Alessandra Marchi, Mirco Gali??, Guido Baroni, Donatella Benati, Mauro Krampera, Annalisa Pasini, Andrea Sbarbati, Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plastic and Reconstructive Surgery. ,vol. 119, pp. 1409- 1422 ,(2007) , 10.1097/01.PRS.0000256047.47909.71
E. Faglia, G. Clerici, J. Clerissi, L. Gabrielli, S. Losa, M. Mantero, M. Caminiti, V. Curci, A. Quarantiello, T. Luppattelli, A. Morabito, Long-Term Prognosis of Diabetic Patients With Critical Limb Ischemia A population-based cohort study Diabetes Care. ,vol. 32, pp. 822- 827 ,(2009) , 10.2337/DC08-1223