THE ANOPHELES ALBIMANUS WHITE GENE : MOLECULAR CHARACTERIZATION OF THE GENE AND A SPONTANEOUS WHITE GENE MUTATION
作者： Zhaoxi Ke , Mark Q Benedict , Anthony J Cornel , Nora J Besansky , Frank H Collins
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摘要: We have cloned and characterized the white gene of Anopheles albimanus. Comparison deduced amino acid sequence this with its homologs from six species Diptera show that An. albimanus is most similar to gambiae (92% identity). A spontaneous white-eyed mutant was caused by an approximately 10 kb insertion into a CT dinucleotide repeat region intron 2 locus. The flanks are long (at least 400 bp), nearly perfect inverted terminal sequences. This should be useful as marker for germ line transformation
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