Molecular Studies of Insect Vectors of Malaria

作者: Julian M. Crampton

DOI: 10.1016/S0065-308X(08)60135-9

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摘要: Publisher Summary This chapter focuses on the molecular studies of insect vectors malaria. The incidence malaria is increasing because development insecticide resistance by mosquito and appearance drug in parasite. These factors are exacerbated migration numbers people from nonendemic areas to regions where prevalent. Research over past century has increased understanding complex relationship among vectors, parasite causing disease, human host. Two applications biology considered relation vector control. first utilization DNA probe technology improve vector-identification techniques. second a completely revolutionary approach control through genetic manipulation anophelines, so as disrupt transmission cycle. Many members sibling species complexes. Sibling reproductively distinct but cannot be distinguished morphological features alone require alternative methods for identification. Despite dramatic advances made recently with respect genome Drosophila melanogaster, there an urgent need much greater disease carriers. must include analysis complexity organization their genomes distribution coding repetitive sequences.

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