The trials and tribulations of clinical trials in the elderly.

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William B. Applegate, Stephen T. Miller, Marshall J. Graney, Janet T. Elam, Robert Burns, Derene E. Akins, A Randomized, Controlled Trial of a Geriatric Assessment Unit in a Community Rehabilitation Hospital New England Journal of Medicine. ,vol. 322, pp. 1572- 1578 ,(1990) , 10.1056/NEJM199005313222205

Laura J. McVey, Effect of a Geriatric Consultation Team on Functional Status of Elderly Hospitalized Patients Annals of Internal Medicine. ,vol. 110, pp. 79- 84 ,(1989) , 10.7326/0003-4819-110-1-79

Christopher A Silagy, John J McNeil, Geoffrey A Donnan, Andrew M Tonkin, Bernard Worsam, Katrina Campion, The Pace Pilot Study: 12-Month Results and Implications for Future Primary Prevention Trials in the Elderly Journal of the American Geriatrics Society. ,vol. 42, pp. 643- 647 ,(1994) , 10.1111/J.1532-5415.1994.TB06864.X

Paul Cotton, Women's Health Initiative Leads Way as Research Begins to Fill Gender Gaps JAMA. ,vol. 267, pp. 469- 473 ,(1992) , 10.1001/JAMA.1992.03480040013002

Maureen M. Henderson, Lawrence H. Kushi, Donovan J. Thompson, Sherwood L. Gorbach, Carolyn K. Clifford, William Insull, Myron Moskowitz, Robert S. Thompson, Feasibility of a randomized trial of a low-fat diet for the prevention of breast cancer: dietary compliance in the Women's Health Trial Vanguard Study. Preventive Medicine. ,vol. 19, pp. 115- 133 ,(1990) , 10.1016/0091-7435(90)90014-B

Thomas M. Vogt, Christine Curtis Ireland, Dennis Black, Greta Camel, Glenn Hughes, Recruitment of elderly volunteers for a multicenter clinical trial: the SHEP pilot study. Controlled Clinical Trials. ,vol. 7, pp. 118- 133 ,(1986) , 10.1016/0197-2456(86)90028-0

William B. Applegate, J. David Curb, Designing and Executing Randomized Clinical Trials Involving Elderly Persons Journal of the American Geriatrics Society. ,vol. 38, pp. 943- 950 ,(1990) , 10.1111/J.1532-5415.1990.TB05713.X

J. Rowe, R. Kahn, Human aging: usual and successful Science. ,vol. 237, pp. 143- 149 ,(1987) , 10.1126/SCIENCE.3299702