Translational discrimination of mRNAs coding for human insulin-like growth factor II.
作者： F.C. Nielsen , S. Gammeltoft , J. Christiansen
DOI: 10.1016/S0021-9258(18)77363-8
关键词:
摘要: Sucrose gradient and Northern analyses were used to study the translational status of endogenous multiple mRNAs encoding prepropeptide for human insulin-like growth factor II. The results showed that a minor 4.8-kilobase mRNA was exclusively engaged in synthesis on membrane-bound polysomes, whereas major 6.0-kilobase present cytoplasmic particle which stable EDTA. We conclude discrimination between is dictated by their different 5'-untranslated regions.
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