Exploring the multifaceted neuroprotective actions of Emblica officinalis (Amla): a review.
作者： Ibraheem Husain , Saima Zameer , Tushar Madaan , Akram Minhaj , Wasim Ahmad
DOI: 10.1007/S11011-019-00400-9
关键词:
摘要: Today, neurological disorders such as epilepsy, depression, tardive dyskinesia, and stress, neurodegenerative Alzheimer's disease, Parkinson's dementia, Huntington's disease affect millions of people all over the world. Existing pharmacological interventions do not meet desired therapeutic benefits for a significant number patients, hence, numerous research studies are in progress to find novel therapies these disorders. Herbal drugs, which have been used traditional medicine centuries, also being explored scientifically evaluated treatment While substantial evidence exists antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-hyperglycemic effects Emblica officinalis, vivo vitro studies, revealed its beneficial activities These diverse neuroprotective pharmacodynamic actions E. officinalis corroborated by accumulating pre-clinical deserve attention scientific community develop viable pharmacotherapeutic strategies. The present review elaborates upon latest pertaining gives way future this area.
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sci-hub.se 参考文章(66)
Mahaveer Golechha, Dharamvir Singh Arya, Jagriti Bhatia, Hydroalcoholic extract of Emblica officinalis Gaertn. affords protection against PTZ-induced seizures, oxidative stress and cognitive impairment in rats. Indian Journal of Experimental Biology. ,vol. 48, pp. 474- 478 ,(2010)
A.V. Muruganandam, Salil K. Bhattacharya, Dipankar Bhattacharya, Effect of Emblica officinalis tannoids on a rat model of tardive dyskinesia. Indian Journal of Experimental Biology. ,vol. 38, pp. 945- 947 ,(2000)
MJ Lawrence, M Heinrich, C Cable, SE Edwards, Where do herbal medicines belong? Part 1 – an overview of CAM The Pharmaceutical Journal , 288 pp. 565-566. (2012). ,(2012)
Dinesh Dhingra, Parul Joshi, Arun Gupta, Ritu Chhillar, Possible involvement of monoaminergic neurotransmission in antidepressant-like activity of Emblica officinalis fruits in mice. CNS Neuroscience & Therapeutics. ,vol. 18, pp. 419- 425 ,(2012) , 10.1111/J.1755-5949.2011.00256.X
Frank M. LaFerla, Kim N. Green, Salvatore Oddo, Intracellular amyloid-β in Alzheimer's disease Nature Reviews Neuroscience. ,vol. 8, pp. 499- 509 ,(2007) , 10.1038/NRN2168
Manish K Singh, Suraj Singh Yadav, Rajesh Singh Yadav, Abhishek Chauhan, Devendra Katiyar, Sanjay Khattri, None, Protective effect of Emblica-officinalis in arsenic induced biochemical alteration and inflammation in mice. SpringerPlus. ,vol. 4, pp. 438- 438 ,(2015) , 10.1186/S40064-015-1227-9
Bondy Brigitta, Pathophysiology of depression and mechanisms of treatment. Dialogues in clinical neuroscience. ,vol. 4, pp. 7- 20 ,(2002) , 10.31887/DCNS.2002.4.1/BBONDY
Frank J.E. Vajda, Neuroprotection and Neurodegenerative Disease Journal of Clinical Neuroscience. ,vol. 9, pp. 4- 8 ,(2002) , 10.1054/JOCN.2001.1027
Manish K Singh, Shailendra Dwivedi, Suraj S Yadav, Praveen Sharma, Sanjay Khattri, None, Arsenic-Induced Hepatic Toxicity and Its Attenuation by Fruit Extract of Emblica officinalis (Amla) in Mice Indian Journal of Clinical Biochemistry. ,vol. 29, pp. 29- 37 ,(2014) , 10.1007/S12291-013-0353-9
Parminder Nain, Vipin Saini, Sunil Sharma, Jaspreet Nain, Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin-induced type-2 diabetes mellitus (T2DM) rats. Journal of Ethnopharmacology. ,vol. 142, pp. 65- 71 ,(2012) , 10.1016/J.JEP.2012.04.014