Physiologic determinants of coronary blood flow during external cardiac massage

摘要: Adequate coronary blood flow is a major determinant for successful resuscitation from cardiopulmonary arrest. To develop compression techniques that optimize flow, we implanted in eight dogs electromagnetic probes measured circumflex and ascending aortic flow. Micromanometers left ventricular pressures. Each dog was anesthetized intubated, the heart fibrillated electrically. High-impulse manual chest compressions were performed with supine position, rate varied 60/min to 150/min. Antegrade occurred primarily during artificial diastole, there brief period of retrograde systole. Cardiac output diastolic pressure increased rate, significantly augmenting peak velocity. However, perfusion time decreased linearly limited at rates greater than 120/min. As result, net high-impulse determined by time. Coronary optimized this model