The low risk of upper gastrointestinal bleeding in patients dispensed corticosteroids
作者： Jeffrey L. Carson , Brian L. Strom , Rita Schinnar , Amy Duff , Ellen Sim
DOI: 10.1016/0002-9343(91)90119-I
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摘要: Abstract purpose: To determine the incidence of upper gastrointestinal bleeding in patients treated with corticosteroids. and methods: The tract was assessed a cohort 19,880 from Michigan Medicaid billing database dermatitis and/ or asthma corticosteroids during 1980 to 1984. frequency within 60 days after each corticosteroid prescription. results: without past history who were exposed only 2.8 cases per 10,000 person-months. rate notably higher receiving anticoagulants those prior (23.0 15.9 person-months, respectively). conclusion: Because ambulatory is so low, prophylactic therapy should be restricted high-risk patients, if it used at all.
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sci-hub.se 参考文章(13)
René Menguy, Gastric mucus and the gastric mucous barrier. A review. American Journal of Surgery. ,vol. 117, pp. 806- 812 ,(1969) , 10.1016/0002-9610(69)90069-5
R W Reifenstein, S J Gray, H M Spiro, The effect of adrenocorticotropic hormone upon uropepsin excretion. Journal of Laboratory and Clinical Medicine. ,vol. 35, pp. 899- 910 ,(1950)
Jeffrey L Carson, Brian L Strom, Keith A Soper, Suzanne L West, M Lee Morse, The Association of Nonsteroidal Anti-inflammatory Drugs With Upper Gastrointestinal Tract Bleeding Archives of Internal Medicine. ,vol. 147, pp. 85- 88 ,(1987) , 10.1001/ARCHINTE.1987.00370010087021
Harold O. Conn, Bennett L. Blitzer, Nonassociation of adrenocorticosteroid therapy and peptic ulcer. The New England Journal of Medicine. ,vol. 294, pp. 473- 479 ,(1976) , 10.1056/NEJM197602262940905
Brian L. Strom, Upper Gastrointestinal Tract Bleeding From Oral Potassium Chloride Archives of Internal Medicine. ,vol. 147, pp. 954- 957 ,(1987) , 10.1001/ARCHINTE.1987.00370050146025
Brian L Strom, Jeffrey L Carson, M Lee Morse, Aida A LeRoy, The computerized on-line Medicaid pharmaceutical analysis and surveillance system: A new resource for postmarketing drug surveillance Clinical Pharmacology and Therapeutics. ,vol. 38, pp. 359- 364 ,(1985) , 10.1038/CLPT.1985.188
Howard M. Spiro, Is the Steroid Ulcer a Myth? New England Journal of Medicine. ,vol. 309, pp. 45- 47 ,(1983) , 10.1056/NEJM198307073090110
H. M. Spiro, S. S. Milles, Clinical and Physiologic Implications of the Steroid-Induced Peptic Ulcer New England Journal of Medicine. ,vol. 263, pp. 286- 294 ,(1960) , 10.1056/NEJM196008112630606
Jeffrey L Carson, Brian L Strom, M Lee Morse, Suzanne L West, Keith A Soper, Paul D Stolley, Judith K Jones, The Relative Gastrointestinal Toxicity of the Nonsteroidal Anti-inflammatory Drugs Archives of Internal Medicine. ,vol. 147, pp. 1054- 1059 ,(1987) , 10.1001/ARCHINTE.1987.00370060050010
Julio Messer, Dinah Reitman, Henry S. Sacks, Harry Smith, Thomas C. Chalmers, Association of Adrenocorticosteroid Therapy and Peptic-Ulcer Disease New England Journal of Medicine. ,vol. 309, pp. 21- 24 ,(1983) , 10.1056/NEJM198307073090105