Amiloride and its analogs as tools in the study of ion transport.

作者: Thomas R. Kleyman , Edward J. Cragoe

DOI: 10.1007/BF01871102

关键词:

摘要: Amiloride inhibits most plasma membrane Na+ transport systems. We have reviewed the pharmacology of inhibition of these transporters by amiloride and its analogs. Thorough studies …

参考文章(72)
R J Davis, M P Czech, Amiloride directly inhibits growth factor receptor tyrosine kinase activity. Journal of Biological Chemistry. ,vol. 260, pp. 2543- 2551 ,(1985) , 10.1016/S0021-9258(18)89586-2
D J Benos, G Saccomani, S Sariban-Sohraby, The epithelial sodium channel. Subunit number and location of the amiloride binding site. Journal of Biological Chemistry. ,vol. 262, pp. 10613- 10618 ,(1987) , 10.1016/S0021-9258(18)61007-5
T R Kleyman, D Landry, A Karlin, E Cragoe, C Ashbaugh, T Yulo, Q Al-Awqati, Photoaffinity labeling of the epithelial sodium channel. Journal of Biological Chemistry. ,vol. 261, pp. 2839- 2843 ,(1986) , 10.1016/S0021-9258(17)35863-5
J M Besterman, W S May, H LeVine, E J Cragoe, P Cuatrecasas, Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange. Journal of Biological Chemistry. ,vol. 260, pp. 1155- 1159 ,(1985) , 10.1016/S0021-9258(20)71221-4
L Simchowitz, O W Woltersdorf, E J Cragoe, Intracellular accumulation of potent amiloride analogues by human neutrophils Journal of Biological Chemistry. ,vol. 262, pp. 15875- 15885 ,(1987) , 10.1016/S0021-9258(18)47670-3