作者: I. Biemond , Irene T. Weterman , J. J. Van Rood , E. C. Klasen , P. Meera Khan
DOI: 10.1007/978-94-009-8273-4_43
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摘要: It is now well established that Crohn’s disease [CD] occurs significantly more frequently in the relatives of patients than general population (1). More over, several families have been reported with one sibling affected CD, and majority monozygous twins so far are concordant for (2). Ankylosing spondylitis, a known genetic background was found to be associated CD expected by chance alone All these arguments suggest predisposition CD. Parameters define susceptibility should bring an enormous advance understanding familial Therefore, we started systematic search markers