Discordant HLA haplotype segregation in familial Crohn's disease

作者: O.E. Eade , C. Moulton , B.R. MacPherson , S.ST. Andre-Ukena , R.J. Albertini

DOI: 10.1016/0016-5085(80)90140-7

关键词:

摘要: To look for possible HLA linkage in familial Crohn's disease, haplotype segregation patterns were determined 70 members of five kindreds, each having 2 or more patients with disease (total number: 13 1 ulcerative colitis). Concordant haplotypes and was not observed. Study A B locus phenotypes 64 additional documented failed to show any significant association. We conclude that these does account the susceptibiltiy antigens are associated disease.

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