作者: Richard H. Duerr
关键词: Human leukocyte antigen 、 Immunology 、 Disease 、 Autoantibody 、 Biology 、 Crohn's disease 、 Family aggregation 、 Concordance 、 Genetics 、 Ulcerative colitis 、 Inflammatory bowel disease
摘要: Summary:Genetic influence in the susceptibility to inflammatory bowel disease (IBD) is suggested by racial, ethnic, and familial aggregation of disease. Increased concordance for IBD monozygotic compared with dizygotic twins suggests that genetic rather than environmental factors are primarily re