Functional Development of Hair Cells in the Mammalian Inner Ear

摘要: Abstract Sensory organs and the neural networks responsible for processing sensory information are supremely well adapted detecting input from external environment. Their challenge is to maximize sensitivity fidelity over a wide dynamic range. Mammalian hair cells process mechanical stimuli sound, movement, gravitational forces with unparalleled temporal precision very low frequency displacements in vestibular system as much 180 kHz auditory system. Here we review current understanding of how mammalian cochlear systems orchestrate functional development mechanoelectrical transduction their apical bundles synaptic transmission through specialized ribbon synapses.