Modulation of motor function and cortical plasticity in health and disease.

摘要: Basic science studies demonstrated mechanisms of plasticity and metaplasticity. More recent human identified some these as operating in multiple areas cognition, such learning memory, functional recovery from lesions the CNS, stroke. One goals neurorehabilitation is translation principles into rational strategies to promote function. Understanding role could lead development therapeutic options situations which there virtually no treatment alternative, chronic We review work performed better understand substrates underlying cortical discuss experimental approaches enhance function, like stimulation.