Ursolic acid, a potential anticancer compound for breast cancer therapy.

摘要: AbstractThere are growing interests in the health benefits associated with consumption of fruits and vegetables, especially for prevention cancer, cardiovascular or other chronic diseases. Epidemiological studies clinical trials suggest that these strongly phytochemicals found vegetables. Ursolic acid is a naturally synthesized pentacyclic triterpenoid, widely distributed different Current research suggested ursolic its derivatives exhibited anticancer activity, anti-inflammatory effects, induction apoptosis several human cancer cells. In particular, inhibited breast proliferation by inducing cell G1/G2 arrest regulating expression key proteins signal transduction pathways. addition, induced cells through intrinsic extrinsic apoptotic was also determined to scavenge free radicals have...