Nonsteroidal Anti-inflammatory Drugs and Risk of Incident Heart Failure: A Systematic Review and Meta-analysis of Observational Studies.
作者： Patompong Ungprasert , Narat Srivali , Charat Thongprayoon
DOI: 10.1002/CLC.22502
关键词:
摘要: Background The association between the development of heart failure (HF) and use nonsteroidal anti-inflammatory drugs (NSAIDs) is not well established. Hypothesis Use NSAIDs may increase risk incident HF. Methods We conducted a systematic review meta-analysis observational studies that reported odds ratio, relative risk, hazard or standardized incidence ratio comparing HF in NSAID users vs nonusers. Pooled ratios (RR) 95% confidence intervals (CI) for all both subclasses (conventional highly selective cyclooxygenase-2 inhibitors [COXIBs]) were calculated using random-effect, generic inverse variance method. Results Seven with 7 543 805 participants identified included our data analysis. Use was associated significantly higher developing HF, pooled RR 1.17 (95% CI: 1.01-1.36). Subgroup analysis showed elevated among conventional (RR: 1.35, 1.15-1.57) but COXIBs 1.03, 0.92-1.16). Conclusions A observed NSAIDs.
sci-hub.se 参考文章(31)
Hassan, What Is The “Safest” Non-Steroidal Anti-Inflammatory Drugs? Current Research in Medicine. ,vol. 3, pp. 115- 123 ,(2012) , 10.3844/AMJSP.2012.115.123
Arduino A. Mangoni, Richard J. Woodman, Paraskevi Gaganis, Andrew L. Gilbert, Kathleen M. Knights, Use of non-steroidal anti-inflammatory drugs and risk of incident myocardial infarction and heart failure, and all-cause mortality in the Australian veteran community British Journal of Clinical Pharmacology. ,vol. 69, pp. 689- 700 ,(2010) , 10.1111/J.1365-2125.2010.03627.X
Steven S. Coughlin, Recall bias in epidemiologic studies Journal of Clinical Epidemiology. ,vol. 43, pp. 87- 91 ,(1990) , 10.1016/0895-4356(90)90060-3
Dirk O. Stichtenoth, Verena Marhauer, Dimitrios Tsikas, Frank-Mathias Gutzki, Jurgen C. Frolich, Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. Kidney International. ,vol. 68, pp. 2197- 2207 ,(2005) , 10.1111/J.1523-1755.2005.00676.X
Muhammad Mamdani, David N Juurlink, Douglas S Lee, Paula A Rochon, Alex Kopp, Gary Naglie, Peter C Austin, Andreas Laupacis, Therese A Stukel, Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: a population-based cohort study. The Lancet. ,vol. 363, pp. 1751- 1756 ,(2004) , 10.1016/S0140-6736(04)16299-5
Bruno H. Ch. Stricker, Johan Feenstra, Eibert R. Heerdink, Diederick E. Grobbee, Association of nonsteroidal anti-inflammatory drugs with first occurrence of heart failure and with relapsing heart failure: the Rotterdam Study. JAMA Internal Medicine. ,vol. 162, pp. 265- 270 ,(2002) , 10.1001/ARCHINTE.162.3.265
Payal Kohli, Ph Gabriel Steg, Christopher P Cannon, Sidney C Smith Jr, Kim A Eagle, E Magnus Ohman, Mark J Alberts, Elaine Hoffman, Jianping Guo, Tabassome Simon, Emmanuel Sorbets, Shinya Goto, Deepak L Bhatt, REACH Registry Investigators, NSAID Use and Association with Cardiovascular Outcomes in Outpatients with Stable Atherothrombotic Disease The American Journal of Medicine. ,vol. 127, pp. 53- 60.e1 ,(2014) , 10.1016/J.AMJMED.2013.08.017
Gary C. Curhan, Andrea J. Bullock, Susan E. Hankinson, Walter C. Willett, Frank E. Speizer, Meir J. Stampfer, Frequency of use of acetaminophen, nonsteroidal anti-inflammatory drugs, and aspirin in US women. Pharmacoepidemiology and Drug Safety. ,vol. 11, pp. 687- 693 ,(2002) , 10.1002/PDS.732
R. J. Campbell, K. B. Sneed, Acute congestive heart failure induced by rofecoxib. Journal of The American Board of Family Practice. ,vol. 17, pp. 131- 135 ,(2004) , 10.3122/JABFM.17.2.131
Andrea D Furlan, Emma Irvin, Claire Bombardier, None, Limited search strategies were effective in finding relevant nonrandomized studies Journal of Clinical Epidemiology. ,vol. 59, pp. 1303- 1311 ,(2006) , 10.1016/J.JCLINEPI.2006.03.004