Analysis of Oligonucleotides and Antisense DNA Analogs

摘要: Single stranded oligonucleotides comprise short strands of both natural and chemically modified nucleic acids. Although there is no fixed terminology, it generally understood that the length synthetic in range 5 to 150 bases. DNA sequencing reaction mixtures contain single oligonucleotides, most often 300 up more than 1000 bases long. In terms separation problem, are not at all different same or similar electrophoretic conditions can be used for types compounds. However, strategies large volume require a unified approach which includes instrumental parameters such as detection multiplexing speed resolution. with CE will discussed Chapter 10.