Exploring miRNA-Associated Signatures with Diagnostic Relevance in Glioblastoma Multiforme and Breast Cancer Patients
作者： Véronique LeBlanc , Pier Morin
DOI: 10.3390/JCM4081612
关键词:
摘要: The growing attention that non-coding RNAs have attracted in the field of cancer research recent years is undeniable. Whether investigated as prospective therapeutic targets or prognostic indicators diagnostic biomarkers, clinical relevance these molecules starting to emerge. In addition, identification a plethora body fluids has further positioned attractive non-invasive biomarkers. This review will first provide an overview synthetic cascade leads production small microRNAs (miRNAs) and presents their strengths biomarkers disease. Our interest next be directed at exploring utility miRNAs two types cancer: brain tumor glioblastoma multiforme (GBM) breast cancer. Finally, we discuss additional implications associated with miRNA detection well introduce other generated community.
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Rouba Ali-Fehmi, Fazlul H Sarkar, Seema Sethi, Sandeep Mittal, Aamir Ahmad, Wei Chen, Up-regulation of microRNA-10b is associated with the development of breast cancer brain metastasis. American Journal of Translational Research. ,vol. 6, pp. 384- 390 ,(2014)
Subramanian Kumar, Ranganathan Keerthana, Annamalai Pazhanimuthu, Pachiappan Perumal, Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients Indian Journal of Biochemistry & Biophysics. ,vol. 50, pp. 210- 214 ,(2013)
Bala Gür Dedeoğlu, High-Throughput Approaches for MicroRNA Expression Analysis miRNomics: MicroRNA Biology and Computational Analysis. ,vol. 1107, pp. 91- 103 ,(2014) , 10.1007/978-1-62703-748-8_6
Ming-fu Wu, Jie Yang, Tao Xiang, Yan-yan Shi, Li-jiang Liu, miR-21 targets Fas ligand-mediated apoptosis in breast cancer cell line MCF-7 Journal of Huazhong University of Science and Technology-medical Sciences. ,vol. 34, pp. 190- 194 ,(2014) , 10.1007/S11596-014-1257-5
Yue-Fei Deng, Zheng-Hao Liu, Chao Li, Bing-Xi Lei, Zhong-Jun Li, miR-21 induces cell proliferation and suppresses the chemosensitivity in glioblastoma cells via downregulation of FOXO1. International Journal of Clinical and Experimental Medicine. ,vol. 7, pp. 2060- 2066 ,(2014)
Eun-Jung Jung, Libero Santarpia, Juyeon Kim, Francisco J. Esteva, Erica Moretti, Aman U. Buzdar, Angelo Di Leo, Xiao-Feng Le, Robert C. Bast, Soon-Tae Park, Lajos Pusztai, George A. Calin, Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients Cancer. ,vol. 118, pp. 2603- 2614 ,(2012) , 10.1002/CNCR.26565
Anneke Brümmer, Jean Hausser, MicroRNA binding sites in the coding region of mRNAs: extending the repertoire of post-transcriptional gene regulation. BioEssays. ,vol. 36, pp. 617- 626 ,(2014) , 10.1002/BIES.201300104
Patrick Roth, Jörg Wischhusen, Caroline Happold, P. Anoop Chandran, Silvia Hofer, Günter Eisele, Michael Weller, Andreas Keller, A specific miRNA signature in the peripheral blood of glioblastoma patients. Journal of Neurochemistry. ,vol. 118, pp. 449- 457 ,(2011) , 10.1111/J.1471-4159.2011.07307.X
Natalie Falkenberg, Nataša Anastasov, Annalisa Schaub, Vanja Radulovic, Manfred Schmitt, Viktor Magdolen, Michaela Aubele, Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221 Oncotarget. ,vol. 6, pp. 8103- 8114 ,(2015) , 10.18632/ONCOTARGET.3516
David N. Louis, WHO classification of tumours of the central nervous system International Agency for Research on Cancer. ,(2007)