Tracking and treating activated T cells.
作者： N.H. Kim , V. Nadithe , M. Elsayed , O.M. Merkel
DOI: 10.1016/S1773-2247(13)50002-5
关键词:
摘要: Upon activation, T cells of various subsets are the most important mediators in cell-mediated immune responses. Activated play an role system related diseases such as chronic inflammatory diseases, viral infections, autoimmune disease, transplant rejection, Crohn diabetes, and many more. Therefore, efforts have been made to both visualize treat activated specifically. This review summarizes imaging approaches selective therapeutics for gives outlook on how tracking treating can be combined into theragnositc agents cells.
elsevier.com
sci-hub.se 参考文章(65)
Rosane Vianna-Jorge, Guilherme Suarez-Kurtz, Potassium channels in T lymphocytes: therapeutic targets for autoimmune disorders? BioDrugs. ,vol. 18, pp. 329- 341 ,(2004) , 10.2165/00063030-200418050-00005
Pozzilli P, Signore A, Ronga G, Chianelli M, Beverley Pc, In vivo labelling of activated T lymphocytes by i.v. injection of 123I-IL2 for detection of insulitis in type 1 diabetes. Progress in Clinical and Biological Research. ,vol. 355, pp. 229- 238 ,(1990)
Arlene H. Sharpe, Gordon J. Freeman, The B7–CD28 superfamily Nature Reviews Immunology. ,vol. 2, pp. 116- 126 ,(2002) , 10.1038/NRI727
P K Jeffery, Pathology of asthma. British Medical Bulletin. ,vol. 48, pp. 23- 39 ,(1992) , 10.1093/OXFORDJOURNALS.BMB.A072537
Ed Palmer, Negative selection--clearing out the bad apples from the T-cell repertoire. Nature Reviews Immunology. ,vol. 3, pp. 383- 391 ,(2003) , 10.1038/NRI1085
P. K. A. Mongini, R. Chizzonite, A. G. Wolitzky, M. K. Gately, B. B. Desai, P. M. Quinn, IL-12 receptor. II. Distribution and regulation of receptor expression. Journal of Immunology. ,vol. 148, pp. 3125- 3132 ,(1992)
Michael A. Lutz, Amy N. Allen, Thomas P. Kole, Paul E. Zarek, Jonathan D. Powell, Yan Zheng, Samuel L. Collins, A role for mammalian target of rapamycin in regulating T cell activation versus anergy. Journal of Immunology. ,vol. 178, pp. 2163- 2170 ,(2007) , 10.4049/JIMMUNOL.178.4.2163
LAURA P Hale, BARTON F Haynes, None, Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation Journal of Immunology. ,vol. 149, pp. 3809- 3816 ,(1992)
Cornelia M Weyand, Jörg J Goronzy, T-cell-targeted therapies in rheumatoid arthritis. Nature Reviews Rheumatology. ,vol. 2, pp. 201- 210 ,(2006) , 10.1038/NCPRHEUM0142
Il-Kang Na, John C. Markley, Jennifer J. Tsai, Nury L. Yim, Bradley J. Beattie, Alexander D. Klose, Amanda M. Holland, Arnab Ghosh, Uttam K. Rao, Matthias T. Stephan, Inna Serganova, Elmer B. Santos, Renier J. Brentjens, Ronald G. Blasberg, Michel Sadelain, Marcel R. M. van den Brink, Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo Blood. ,vol. 116, ,(2010) , 10.1182/BLOOD-2009-12-259432