作者: Robert J. Simister , Mary A. McLean , Gareth J. Barker , John S. Duncan
DOI: 10.1016/J.EPLEPSYRES.2007.03.001
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摘要: The effect of the antiepileptic medication sodium valproate (VPA) on concentrations cerebral metabolites was studied longitudinally in ten patients with epilepsy using proton magnetic resonance spectroscopy (MRS). Myo-inositol found to be lower while taking VPA, although no relationship between change metabolite concentration, VPA dose or seizure control observed. MRS findings should interpreted light administered medications.