A Physico-chemical Basis for Anion, Cation and Proton Distributions between Rat-liver Mitochondria and the Suspending Medium

摘要: The distribution of ions, including protons, between the mitochondrial interior and medium can be treated, most simply, as a physicochemical problem akin to that met with in cell suspensions, particularly when sufficient is known about system. More now properties, aim present review summarize evidence, some new much derived from earlier reports, distributions permeant anions protons exterior provide an example Gibbs—Donnan law applied situation ionized internal buffer. This only hold course metabolic fluxes are low. Some behave non-penetrants so take on any ratio. cations Ca2+ K+ subject energy-linked inward transport.