Regional T2 and sodium concentration estimates in the normal human brain by sodium-23 MR imaging at 1.5 T.

摘要: Abstract We have analyzed multiple spin echo Na magnetic resonance (MR) images of the normal human brain in four volunteer subjects. Utilizing much slower T2 decay CSF, we obtained that separate cortex from surrounding CSF and measured regional cortex, white matter, vitreous humor, superior sagittal sinus. Assuming a sodium concentration 145 mM normalized extrapolated equilibrium magnetization (M0) for each region to M0 humor estimate concentration. found measurements more consistently distinguish high signal regions blood than do our estimates, whereas estimates adequately matter cortex. The values on other hand, are nearly identical. Our work addresses problems encountered establishing norms clinical application MR represents step toward those norms.