A New Method to Measure Cellular Toxicity of Non-Fibrillar and Fibrillar Alzheimer's Aβ Using Yeast
作者： Prashant Bharadwaj , Lynne Waddington , Jose Varghese , Ian G. Macreadie
关键词: Viability assay 、 Biophysics 、 Yeast 、 Amino acid 、 P3 peptide 、 Extracellular 、 Fibril 、 Biology 、 Toxicity 、 Biochemistry 、 Amyloid
摘要: … yeast. We show that extracellular, non-fibrillar Aβ causes a dose dependent loss of cell viability while fibrillar Aβ has low toxicity… 20 h of incubation with yeast cells. This clearly indicated …
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