Studies on a new proteolytic enzyme from Achromobacter lyticus M497-1 II. Specificity and inhibition studies of Achromobacter protease I
作者： Takeharu Masaki , Toshiyuki Fujihashi , Keiji Nakamura , Masami Soejima
DOI: 10.1016/0005-2744(81)90107-8
关键词:
摘要: The unique specificity of Achromobacter protease I for lysine residue was investigated using synthetic and natural substrates, i.e., derivatives, arginine vasopressin, substance P, ACTH insulin. enzyme cleaved only the -Lys-X- bonds in above substrates. binding affinity alkylamines as determined by Ki much stronger than that corresponding alkylguanidines.
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